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Peptidomimetics

 

ASINEX has been continuously improving the design of small molecules that can effectively mimic biologically relevant di- and tripeptide motifs and can serve as topological mimics of the peptide secondary structures: alpha helixes, beta turns and beta strands/sheets. Our approach is based on the identification of conformationally constrained saturated cyclic scaffolds containing multiple minimalist peptidomimetic pharmacophores. Each scaffold contains 3 points of diversity which are used for introduction of the lipophilic or hydrophilic side chains. The updated peptidomimetic library is now represented by:

Cyclic Polyether Scaffolds
Macrocyclic Scaffolds
Spiro- & Fused 3D-rich Scaffolds

ASINEX's Peptidomimetic Compound Libraries are only available upon request, please contact us at:
Tel.: +7 (495) 780 34 15, +7 (495) 780 34 17
E-mail : LSadovenko@asinex.com or Busdev@asinex.com

 

 

 
 
 
 
 
 
 
 
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