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Pre-weighted Sets

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Pre-weighted Sets

ASINEX has several high quality pre-weighted sets on offer. These sets have not prepared from a mother solution that undergoes a freeze-thaw cycle every time a new order is placed. The compounds have either been hand-weighed using dry powder or freshly prepared from DMSO and frozen (just one freeze-thaw cycle).

We have several sets available from all our library ranges, including Gold and Platinum, Synergy, Elite and BioDesign. These compounds are available at significantly lower per compound prices compared in comparison to our standard price list.

Library Source	Number of Compounds	Format	Files	Location
Gold and Platinum	12,000	Dry Film	SD File (2.87 Mb)	USA
Platinum	20,000	Dry Powder	SD File (5.61 Mb)	Moscow
Gold and Platinum	26,000	Dry Powder	SD File (6.84 Mb)	Moscow
Synergy	25,000	Dry Film	SD File (5.56 Mb)	USA

Library Source	Number of Compounds	Format	Files	Location
Elite	3,000	Dry Film	SD File (870 Kb)	Moscow
Elite Diverse	17,500	Dry Film / DMSO	SD File (4.09 Mb)	USA
Elite Data	21,000	Dry Film / DMSO	SD File (5.49 Mb)	Moscow / USA
All Elite	81,000	Dry Powder	SD File (20.8 Mb)	Moscow
BioDesign 2008	14,000	DMSO	upon request	Moscow

The 'Elite Data' set

We would like to single out 'Elite Data' set as this set represents a selection of compounds from ASINEX's Elite libraries that has experimental ADMET and solubility data.

	Cut-off	% of set tested	Additional Info
PBS Solubility	>15 µg/mL >15 µg/mL (85% > 100ug/mL)	100%	HTS Nephelometry (8 concentrations/ duplicate/ compound)
CYP Inhibition	60% at 10 µM	50%	CYP-450 panel: 1A2, 2C9, 2C19, 2D6, 3A4
P-gp efflux	< 50% inhibit of P-gp efflux	Representative clusters	-
PAMPA	> 5% PAMPA flux	Representative clusters	-

If you would like to receive more information about any of these sets or require a password for downloading the Elite Libraries based sets (BioDesign only upon request). Please contact busdev@asinex.com.

Additionally, we have many diverse sets and targeted libraries which have been pre-selected, but have to be weighed. Please visit our download zone to see some of these sets.