ASINEX has developed BioDesign and BioMimetic platforms that facilitate the discovery of novel regulators of pharmacologically-relevant “difficult” targets and biological pathways such us Protein-Protein interactions, Lipid GPCRs, Ion Channels, Oncogenic cascades and Epigenetics.
Our technology is based on innovative proprietary chemistries enabling the synthesis of drug-like Macrocycles, non-peptoid Peptide Mimetics and Natural Product-like pharmacophore-rich compounds with experimentally controlled lipophilicity, solubility and chemical stability properties.
The BioDesign and Biomimetic approaches provide an access to novel molecules with a higher level of saturation, three-dimensionality and natural product-like properties. Our synthetic methodology involves strategic use of stereoselective reactions both for scaffold generation and final compound production.
Our most recent novel design concept is the BioMimetic Library. Natural product structures, along with the mechanisms of their biosynthesis, have been an invaluable source of inspiration. Skeletally and functionally diverse natural product derivatives have been designed in order to further advance ASINEX's portfolio of BioDesign compound arrays by exploiting a biomimetic synthetic approach.
Quality is the most important component of all our products and services. We promptly deliver our products to support the efficiency and advancement of your research programs. Our compound libraries and building blocks are of high purity (guaranteed minimum 90%, average 95%) confirmed by HPLC/MS and NMR data which is available on request. We are willing to accommodate any packaging and delivery format you specify as we have over 20 years of experience in formatting orders to the specification of our clients.
ASINEX provides the following complementary early drug discovery services:
We are committed to providing professional resources and dedicated management to ensure maximum productivity and cost-effectiveness leading to successful completion of your project.
- exclusive library design and synthesis;
- computational chemistry;
- bio assay development and screening;
- compound management & quality control.