Ion-Channel

Product Name: Format/SizeDescriptionsDownload
Ion-Channel Library10731 compounds
For cherry-picking
Update: 2018-01
The file contains all available Ion-Channel compounds selected from our Signature & BioDesign Libraries. For more information, please download >>>sdf-icon pdf-icon
SL#005, 051
Ion Channel Modulators. Nav1.8
80 compounds x 2
Pre-Plated Set
Release: 2016
Based on the analysis of several known NaV1.8-blockers ASINEX has developed a pharmacophore model which has been used to carry out an exhaustive search on a 20000+ set of natural product-like compounds. The highest scoring compounds were screened in vitro in the human Nav1.8/β3 sodium channel cell line.
Structures are available,"click here"and downlaod "File#1 (1/5) Signature Libraries.
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SL#092
Ion Channel Modulators Nav1.7
80 compounds
Pre-Plated Set
Release: 2018
Structures are available,"click here"and downlaod "File#1 (1/5) Signature Libraries.
SL#041
Voltage-gated sodium channels
80 compounds
Pre-Plated Set
Release: 2016
ASINEX has identified a number of ion-channel modulators against undisclosed voltage-gated ion channels. This library is useful for ion channel research and drug discovery.
Structures are available,"click here"and downlaod "File#1 (1/5) Signature Libraries.
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SL#064
TMEM16A Channel Modulators
80 compounds
Pre-Plated Set
Release: 2017
Transmembrane protein 16A (TMEM16A) inhibitors have been proposed for treatment of disorders of epithelial fluid and mucus secretion, hypertension, asthma, and possibly cancer. A recent study revealed that a series of 2-acylaminocycloalkylthiophene-3-carboxylic acid arylamides can inhibit TMEM16A at low nM concentrations. 80 close analogs of the most potent inhibitor 10bm were included into this library.
Structures are available,"click here"and downlaod "File#1 (1/5) Signature Libraries.
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SL#081
Aankyrin-like receptor family
(TRPA1) Agonists 
80 compounds
Pre-Plated Set
Release: 2018
SL#084
Inhibitors of TRPC3/6/7    
80 compounds
Pre-Plated Set
Release: 2018

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