|Asinex Fragments||21872 Compounds|
|ASINEX’s fragments encompass tremendous diversity of our scaffold and synthetic handles that allows straightforward progress from fragments to leads. The subsets of fragments suitable for specific biochemical and/or biophysical screening methods are available upon request.|
|Asinex Building Blocks||26377 Compounds|
|ASINEX’s building block encompasses the legacy of our synthetic know-how and 20+ years of medicinal chemistry expertise with an ultimate goal of delivering novel, valuable chemical monomers for increasingly challenging drug discovery programs.|
In addition to commonly popular functionalities, ASINEX building blocks represent the diversity of other valuable functional groups including alkenes, epoxides, amino alcohols and polyfunctional entities, which are especially useful for template-based generation of compound libraries where a polyfunctional building block can serve as a core scaffolding structure.
ASINEX Building Blocks have been validated for both chemical stability and reactivity. Many of these building blocks have been utilized for the synthesis of our natural product-like and macrocyclic libraries as well as for advancing a number of hit-to-lead optimization projects.