Lead Optimization

ASINEX offers an integrated platform of biology and chemistry skills for hit to lead expansion and lead optimization. We can optimize hits from a multitude of sources and offer an especially fast service for ASINEX's in-house designed compounds. ASINEX can provide design input for template modification and decoration based on known leads and SAR analysis.

Our chemists with the aid of our computational and biology teams are able to optimize the following parameters: Intellectual Property, Toxicity, Solubility, Permeability, Metabolism, hERG Electrophysiology etc. ASINEX has a special collection of 2000 highly novel peripheral building blocks which are ideal for improving the previously mentioned parameters.

To date ASINEX has completed more than 400 chemistry projects for 50 customers. Please see our press releases and collaborations page for more info.

Please send your enquires to

HQ Switchboard: +7 495 780 3410
HQ Business Development: +7 495 780 3417

ASINEX USA: +1 877 ASINEX1 or +1 336 721 1617
ASINEX Japan: +81-44-400-4428 or +81-80-3401-9097

Once your enquiry has been received by an ASINEX representative, your information will be held in the strictest confidence and you will be contacted within 24 hours. For a detailed quote we usually require 3 working days.