en

Antibacterial


Product Name: Format/Size Descriptions Download
Antibacterial Library 5968 compounds
For cherry-picking
Update: 2020-07
ASINEX has developed a unique compound library for antibacterial research based on the proprietary natural product-like scaffolds that provide great skeletal diversity combined with the presence of polar functional groups and multiple stereogenic centers.
SL#013
Gram Negative Antibacterials
80 compounds
Pre-Plated Set
Release: 2016
ASINEX has created a library of small molecule compounds based on an “iminosugar” scaffold. The selected molecules occupy a very specific physicochemical space of known Gram negative antibiotics. We have also screened this library against 4 selected bacterial pathogens. Several active compounds inhibited >50% of bacterial growth at a given concentration.
SL#062
Microbialb-glucuronidase inhibitors
80 compounds
Pre-Plated Set
Release: 2017
In mice models, several potent (sub-mM) inhibitors of bacterial b-glucuronidases have shown that they significantly reduce the GI damage caused by chemotherapeutic agents. Specifically, several qunoline-containing thioureas demonstrated robust selectivity toward bacterial b-glucuronidases over the human enzyme orthologs with accompanying efficacy in vivo. 80 close analogs of the reported inhibitors have been included in this library.
SL#068
Bacterial riboswitch inhibitors
80 compounds
Pre-Plated Set
Release: 2017
A group from Merck Research Laboratories published a series of structurally related compounds called “ribocils” – small molecules that target the riboflavin riboswitch. These compounds demonstrate potent antibacterial activity and inhibit riboflavin, flavin mononucleotide and flavin adenine dinucleotide synthesis - essential cofactors of bacterial metabolism. 80 close structural analogs of one of the “ribocils” have been included in this library.
Contact
Global

Ludmila Sadovenko

lsadovenko@asinex.com
North America

Mark Parisi

mparisi@asinex.com

Toll Free: +1 877 ASINEX1

Tel: +1 336 721 1617

Fax: +1 336 721 1618

N.Chestnut St., Ste.104

Winston-Salem, NC 27101

USA

Europe

Galina Afanasyeva

gafanasyeva@asinex.com

Tel: +31 (0) 203416183

Klaprozenweg 75C, 1033NN

Amsterdam, The Netherlands

Japan

Shingo Ota

sota@asinex.com

Tel: 080-3401-9097

30-2 Higashihazu, Nishio,

Aichi Japan

Cart
Your cart is empty
Order
$
0
Checkout
Thanks for your order
We will contact you shortly