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Macrocyclic Intermediates for DEL

Macrocyclic Intermediates are highly attractive chemotypes for the creation of unique DNA-encoded libraries for screening against both emerging and traditional drug targets. At ASINEX, we have combined our expertise in medicinal chemistry and cellular permeability to create multiple polyfunctional Macrocyclic Intermediates. These Intermediates are used as a starting point in the DNA-encoded synthesis sequence and determine the scaffold diversity of the screening library. Our first generation of Macrocyclic Intermediates for DEL (MacroDELTM) is based on diamino acids as such a combination of functional groups facilitates orthogonal protection and ensures the availability of at least 3 vectors for DNA-tag attachment and subsequent combinatorial decoration. There are many credible protocols in literature for the derivatization of amino acids in the presence of DNA which makes our macrocycles a practical and affordable solution for creative DEL design.
Please visit our online catalog for available Macrocyclic Intermediates or contact our customer support team for any additional information.



LAS 99909566
LAS 99909566
50 mg
$950
add
LAS 99914969
LAS 99914969
50 mg
$950
add
LAS 99914970
LAS 99914970
50 mg
$950
add
LAS 99914971
LAS 99914971
50 mg
$950
add
LAS 99915022
LAS 99915022
50 mg
$1830
add
LAS 99915023
LAS 99915023
50 mg
$1830
add
LAS 99915024
LAS 99915024
50 mg
$1830
add
LAS 99915025
LAS 99915025
50 mg
$1830
add
LAS 99915026
LAS 99915026
50 mg
$1830
add
LAS 99915027
LAS 99915027
50 mg
$1830
add
LAS 99915028
LAS 99915028
50 mg
$1830
add
LAS 99915029
LAS 99915029
50 mg
$1830
add
Contact
Global

Ludmila Sadovenko

lsadovenko@asinex.com
North America

Mark Parisi

mparisi@asinex.com

Toll Free: +1 877 ASINEX1

Tel: +1 336 721 1617

Fax: +1 336 721 1618

N.Chestnut St., Ste.104

Winston-Salem, NC 27101

USA

Europe

Galina Afanasyeva

gafanasyeva@asinex.com

Tel: +31 (0) 203416183

Klaprozenweg 75C, 1033NN

Amsterdam, The Netherlands

Japan

Shingo Ota

sota@asinex.com

Tel: 080-3401-9097

30-2 Higashihazu, Nishio,

Aichi Japan

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